Antimicrobial Therapy

Antimicrobial Therapy

The development of antibiotics has been one of the greatest achievements in medical history because they minimize the effects of many and often serious life-threatening infectious diseases.

The broad range of the existing antibiotics offers the physician the possibility to choose the most appropriate for each case. There are two methods in order to treat an infection: the rational and the empirical one. The former presupposes the isolation of the pathogen agent and the administration of the appropriate antibiotic according to the sensibility of the microbial strain and the pharmacokinetic properties of the medicinal product.

As far as the latter is concerned (empirical chemotherapy), the therapist acts on the strength of experience and international or national guidelines, without knowing precisely the pathogen agent.

The most widely applicable strategy for every infection consists of taking material for culture before starting the treatment, immediate start of the empirical chemotherapy and possible revision after the results of the culture if the pathogen agent is detected.

The resistance of the pathogen microbes due to the excessive use of antibiotics consists of a serious problem for the medical community, as the antibiotics become practically useless.

Therefore, the administration of the antibiotics should be moderate and the patient should follow exactly the instructions of the physician.


  • Λοιμώξεις και αντιμικροβιακή χημειοθεραπεία, Ελένη Γιαμαρέλλου & συνεργάτες (Infections and antimicrobial chemotherapy, Eleni Giamarellou & collaborators)
  • ΕθνικόσυνταγολόγιοΕΟΦ (National Prescription Book- National Organization for Medicines)

International Health Organizations:

European Respiratory Society

World Health Organization (WHO)

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