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Gastroenterology

Gastroenterology

The peptic ulcer and the gastroesophageal reflux, which worry many people in the developed countries as well as in the developing countries, are the main diseases of the digestive system.

The H-2 antagonists (inhibitors of the H2 receptors of histamine), which were usually administered against the diseases of the digestive system, have been replaced during the last decade by the Proton Pump Inhibitors (PPIs) which reduce the gastric acid production.

Moreover, the administration of a proton pump inhibitor combined with a double dosage schedule of antibiotics results to the eradication of the H. pylori (spiral bacterium that inhabits the stomach and the duodenum, responsible for the development of ulcers) for 96% of the cases, offering relief to people with duodenal and gastric ulcers.

Unfortunately, factors such as stress, fast food consumption and smoking are responsible for gastrointestinal troubles as the syndrome of gastroesophageal reflux, which occurs when acid stomach contents back up into the oesophagus, causing heartburn and damages of the oesophagus.

The research for the discovery of new products is very important in order to confront more diseases of the digestive system which harass more and more people, mainly due to the modern lifestyle.

Bibliography:
Medline Plus

International Health Organizations:

European Society of Gastrointestinal Endoscopy

American Gastroenterological Association

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